临床双聘教授
代表文章:
1. Sun J, Roy S. Gene-based therapies for neurodegenerative diseases. Nature Neuroscience, 2021 Mar;24(3):297-311.(影响因子:28.771)
- 文章被国际阿尔兹海默论坛(ALZFORUM)、Nature期刊等推荐
2. Sun J, Carlson-Stevermer J, …, McLean P, Sproul A, Saha K, Roy S. CRISPR/Cas9 editing of APP C-terminus attenuates beta-cleavage and promotes alpha-cleavage. Nature Communications, 2019 Jan 3;10(1):53.(影响因子:17.694)
- 文章被国际阿尔兹海默论坛 (ALZFORUM)、Nature Communications 期刊等推荐
3. Sun J, Wang L, Bao H, Premi S, Das U, Chapman E, Roy S. Functional cooperation of alpha-synuclein and VAMP2 in synaptic vesicle recycling. Proc Natl Acad Sci USA, 2019 Jun 4;116(23):11113-11115.(影响因子:12.779)
4. Sun J, Pan CQ, Chew TW, Liang F, Burmeister M, Low BC. BNIP-H Recruits the Cholinergic Machinery to Neurite Terminals to Promote Acetylcholine Signaling and Neuritogenesis. Developmental Cell, 2015 Sep 14;34(5): 555-68.(影响因子:13.417)
-文章被ScienceDaily, Friedreich’s Ataxia, The Straits Times News等国际媒体推荐
5. Sun J, Prabhu N, Tang J, Yang F, Jia L, Guo J, Xiao K, Tam WL, Nordlund P, Dai L. Recent advances in proteome‐wide label‐free target deconvolution for bioactive small molecules. Medicinal Research Reviews, 2021 Nov;41(6):2893-2926.(影响因子:12.388)
6. Zhang W*, Xu C*, Sun J*, Shen H, Wang J, Yang C. Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential. Acta Pharmaceutica Sinica B, 2022 March; 12(3):1019-1040.(共同一作,影响因子:14.903)
7. Wu J*, Sun X*, Wu C*, Hong X*, Xie L, Shi Z, Zhao L, Du Q#, Xiao W#, Sun J#, Wang J#. Single-cell transcriptome analysis reveals liver injury induced by glyphosate in mice. Cell Mol Biol Lett, 2023 Feb 4;28(1):11. (共同通讯,影响因子:8.71)
8. Yang J, Zhang W, Zhang S, Iyaswamy A, Sun J#, Wang J#, Yang C#. Novel Insight into Functions of Transcription Factor EB (TFEB) in Alzheimer’s Disease and Parkinson’s Disease. Aging and Disease, 2022, Dec 3. (共同通讯,影响因子:9.97)
9. Sun J, Roy S. The physical approximation of APP and BACE-1: A key event in Alzheimer’s disease pathogenesis. Developmental Neurobiology, 2018 Mar;78(3): 340-347. (影响因子:3.102)
授权专利:
Roy S and Sun J; Gene-editing based Method of Attenuating the Beta-Amyloid Pathway,2021 Nov 16,美国,US 11,173,216 B2