临床双聘教授

发表文章

1. Zhang Q, Wei T, Jin W, Yan L, Shi L, Zhu S, Bai Y, Zeng Y, Yin Z, Yang J, Zhang W, Wu M, Zhang Y, Peng G, Roessler S, Liu LP. Deficiency in SLC25A15, a hypoxia-responsive gene, promotes hepatocellular carcinoma by reprogramming glutamine metabolism. J Hepatol. 2024 Feb;80(2):293-308. （中科院一区，IF 33.0，最后通讯）

2. Zhang Q, Zhang Y, Fu C, He X, Huang Z, Wu G, Wei T, Jin W, Yan L, Wu M, Peng G, Fan L, Li M, Guo Y, Bi J, Bai Y, Roessler S, Yan GR, Liu LP. CSTF2 Supports Hypoxia Tolerance in Hepatocellular Carcinoma by Enabling m6A Modification Evasion of PGK1 to Enhance Glycolysis. Cancer Res. 2025 Feb 1;85(3):515-534. （中科院一区，IF 16.6，最后通讯）

3. Zhang Q, Wei T, Yan L, Zhu S, Jin W, Bai Y, Zeng Y, Zhang X, Yin Z, Yang J, Zhang W, Wu M, Zhang Y, Liu LP. Hypoxia-Responsive lncRNA AC115619 Encodes a Micropeptide That Suppresses m6A Modifications and Hepatocellular Carcinoma Progression. Cancer Res. 2023 Aug 1;83(15):2496-2512. （中科院一区，IF 16.6，最后通讯）

4. Zhang Q, Xiong L, Wei T, Liu Q, Yan L, Chen J, Dai L, Shi L, Zhang W, Yang J, Roessler S, Liu LP. Hypoxia-responsive PPARGC1A/BAMBI/ACSL5 axis promotes progression and resistance to lenvatinib in hepatocellular carcinoma. Oncogene. 2023 May;42(19):1509-1523. （中科院一区，IF 7.3，最后通讯）

5. Chen Shiyou#, Xing Chenyang#, Huang Dazhou, Zhou Chuanhong, Ding  Bo, Guo Ziheng, Peng  Zhengchun, Wang  Dou , Zhu  Xi, Liu  Shuzhen, Cai  Zhen, Wu  Jieyu, Zhao  Jiaqi, Wu  Zongze, Zhang  Yuhua, Wei  Chaoying, Yan  Qiaoting, Wang  Hongzhong , Fan  Dianyuan, Li-ping Liu* , Zhang Han*,Cao Yihai*, Eradication of tumor growth by delivering novel photothermal selenium-coated tellurium nanoheterojunctions, Science Advanced, 2020 Apr 8, 6(15):eaay6825.（IF=13.116）

6. Dou Wang, Chenchen Ge, Weiyuan Liang, Qinhe Yang, Quan Liu, Wei Ma, Lulin Shi, Hong Wu, Yuhua Zhang, Zongze Wu, Chaoying Wei, Luodan Huang, Zhiyuan Fang,* Li-ping Liu*,Shiyun Bao,* Han Zhang*, In Vivo Enrichment and Elimination of Circulating Tumor Cells by Using a Black Phosphorus and Antibody Functionalized Intravenous Catheter, Advanced Science, 2020, 2000940（IF= 15.804）

7. Xie Jianlei, Fan Taojian ,Ji Hyeon Kim , Xu Yunjie , Wang Yingwei ,Qiao Liang Weiyuan ,Qiao Lijun, Wu Zongze, Liu Quan , Hu Weibin , Yin Na , Yang Ling , Li-ping Liu* ,Jong Seung Kim* , Zhang Han*, Emetine‐Loaded Black Phosphorus Hydrogel Sensitizes Tumor to Photothermal Therapy through Inhibition of Stress Granule Formation, Adv. Funct. Mater.,2020, 30, 2003891.（IF=16.836）

8. Liu Quan, Xie Zhongjian, Qiu Meng, Inseob Shim, Yang Yunlong, Xie Sisi,Yang Qinhe ,  Wang Dou, Chen Shiyou, Fan Taojian, Ding Bo, Guo Ziheng,  Dickson Adah, Yao Xinhuang, ZhanYuhuag, Wu Hong, Wu Zongze, Wei Chaoying ,Wang Hongzhong , Hyeong Seok Kim, Zou Qingshuang, Yan Qiaoting, Cai Zhen, Jong Seung Kim*, Li-ping Liu* , Zhang Han* , Cao Yihai*,Prodrug‐Loaded Zirconium Carbide Nanosheets as a Novel Biophotonic Nanoplatform for Effective Treatment of Cancer, Advanced Science,2020, 7, 2001191.（IF=15.840）

9. Liu Quan, Duo Yanhong, Fu Jianye, Qiu Meng, Sun Zhe, Dickson Adah, Kang Jianlong,  Xie Zhongjian, Fan Taojian, Bao Shiyun, Zhang Han*, Li-ping Liu*, Cao Yihai*, Nano- immunotherapy: Unique mechanisms of nanomaterials in synergizing cancer immunotherapy, Nano Today, Volume 36,2021,101023.（IF= 16.907）

10. Yingwei Wang, Jianlei Xie, Jianlong Kang, Wonseok Choi, Paramesh Jangili, Bin Zhang,Ni Xie, Guohui Nie, Jun He, Han Zhang,* Liping Liu,* and Jong Seung Kim*，Smart Acid-Activatable Self-Assembly of Black Phosphorous as Photosensitizer to Overcome Poor Tumor Retention in Photothermal TherapyAdv. Funct. Mater. 2020, 2003338. （IF=16.836）

11. Liang Weiyuan; Wang Dou; Ren Xiaohui; Ge Chenchen; Wang Hanyue; Li Zhongjun; Liu  Quan; Qiu Meng ; Du Zhiyong ; Qi Xiang ; Xu Yijun*; Liu Liping*; Bao Shiyun*; Zhang Han*; (2020); Facile sonochemical-assisted synthesis of orthorhombic phase black phosphorus/rGO hybrids for effective photothermal therapy, Nanophotonics. 9. 10.1515/nanoph-2019-0476.（IF= 7.491）

12. Liu Quan#, Fan Dahua#,Dickson Adah#, Wu Zhengzhi, Liu Renyan, Yan Qiaoting,Zhang Yue , Du Zhiyong, Wang Dou, Li Yan, Bao Shiyun*, Liu Liping*．CRISPR/Cas9-mediated hypoxia inducible factor-1α knockout enhances the antitumor effect of transarterial embolization in hepatocellular carcinoma, Oncology Reports,2018,40(5).（IF= 3.041）

13. Wang Dou#; Ge Chenchen# ; Lv Kongpeng ; Liu Quan ; Liu Liping*; Yang Qinhe*; Bao Shiyun*; A simple lateral flow biosensor for rapid detection of lead(II) ions based on G-quadruplex structure-switching, Chemical Communication, 2018, 54, 13718.（IF= 6.290）

14. Liu Quan#; Fan Taojian#; Zheng Yuanyuan#; Yang Shengli#; Yu Zhiqiang; Duo Yanhong; Zhang Yuhua; Adah Dickson; Shi Lulin; Sun Zhe; Wang Dou; Jianlei Xie; Wu Hong; Wu Zongze; Ge Chenchen; Qiao Lijun ; Wei Chaoying; Huang Luodan; Yan Qiaoting; Qinhe Yang*; Shiyun Bao*; Liu LiPing *; Han Zhang*; Immunogenic exosome-encapsulated black phosphorus nanoparticles as an effective anticancer photo-nanovaccine. Nanoscale, 2020, 12, 19939.（IF= 6.895）

15. Zhang Qiangnu#; Qiao Lijun#; Liao Juan; Liu Quan; Liu Pengyu; Liu Liping*; A novel hypoxia gene signature indicates prognosis and immune microenvironments characters in patients with hepatocellular carcinoma, J Cell Mol Med, 2021, DOI: 10.1111/jcmm.16249.（IF=4.486）

16. Quan Liu# , Dahua Fan#, Dickson Adah#, Zhengzhi Wu, Renyan Liu, Qiao- Ting Yan, Yue Zhang, Zhi-Yong Du, Dou Wang, Yan Li, Shi-Yun Bao*, Liu Liping*, CRISPR/Cas9 mediated hypoxia inducible factor 1α knockout enhances the antitumor effect of transarterial embolization in hepatocellular carcinoma, Oncology Report, 2018, 40(5):2547-2557. (IF= 3.041)

17. Chenyang Xing#, Shiyou Chen#, Meng Qiu, Xin Liang, Quan Liu, Qingshuang Zou,Zhongjun Li, Zhongjian Xie, Dou Wang, Biqin Dong, Liu Liping*, Dianyuan Fan,and Han Zhang*. Conceptually Novel Black Phosphorus/Cellulose Hydrogels as Promising Photothermal Agents for Effective Cancer Therapy. Advanced Healthcare Materials. 2018 Apr;7(7):e1701510. (封面文章，IF= 5.110)

18. Zhongjian Xie#, Dou Wang#, Taojian Fan#, Chenyang Xing, Zhongjun Li, Wei Tao*, Liu Liping *, Shiyun Bao*, Dianyuan Fan, and Han Zhang*. Black Phosphorus analogue Tin Sulfide Nanosheets: Synthesis and Application as Near-Infrared Photothermal Agents and Drug Delivery Platforms for Cancer Therapy. Journal of Materials Chemistry B, 2018; 6(29):4747-4755. (IF= 4.543)

19. Liu Liping #, Baoguang Hu#, Caiguo Ye#, Ho RL, Rocky L.K. Ho, George G. Chen*, Paul B.S. Lai, HBx mutants differentially affect the activation of hypoxia-inducible factor-1a in hepatocellular carcinoma, British Journal of Cancer, 2014, 110(4):1066-1073.（IF= 6.176）

20. Su SG, Yang M, Zhang MF, Peng QZ, Li MY, Li-ping Liu*, Bao SY. miR-107-mediated decrease of HMGCS2 indicates poor outcomes and promotes cell migration in hepatocellular carcinoma. Int J Biochem Cell Biol. 2017;91(Pt A):53-59. （IF= 3.505）

21. Sheng-li Yang#, Chao Yu#, Jian-xin Jiang*, Li-ping Liu*, Xiefan Fang, Chao Wu, Hepatitis B virus X protein disrupts the balance of circadian rhythm genes expression in hepatocellular carcinoma, Oncology Letters, 2014, 8(6):2715-2720.（IF=1.390）

22. Wan He#, Chang Zou#, Zhong-kai Tian, Wen-yong Tan, Wei-xi shen, Jing-hua Chen, Li-ping Liu*, rui-lian Xu*. Nasopharyngeal carcinoma treated with bevacizumab combined with paclitaxel liposome plus cisplatin: a case report and literature review, Onco Targets Ther, 2016, 20(10):67-72.（IF= 2.612）

23. Caiguo Ye#, Li-ping Liu#, George G. Chen#*, Xiaolin Tang, Zhiwei He, Ming-liang He#, Paul BS Lai*, ZBP-89 reduces histone deacetylase 3 by degrading IkappaB in the presence of Pin1, J Transl Med. 2015, 13(1):23.（IF=3.786）

24. Bao-guang Hu#, Li-ping Liu#, George G. Chen#*, Caiguo Ye, Kevin K.C. Leung, Rocky L.K. Ho, Marie C. Lin, Paul B.S. Lai. Therapeutic efficacy of improved α-fetoprotein promoter-mediated tBid delivered by folate-PEI600-cyclodextrin nanopolymer vector in hepatocellular carcinoma, Exp Cell Res, 2014, 324(2):183-191.（IF=3.546）

25. Sheng-li Yang#, Li-ping Liu#, Jian-xing Jiang*, Zhi-fang Xiong*, Qian-jing He, Cang Wu, The Correlation of Expression Levels of HIF-1α and HIF-2α in Hepatocellular Carcinoma with Capsular Invasion, Portal Vein Tumor Thrombi and Patients' Clinical Outcome, Jpn J Clin Oncol, 2014, 44(2):159-167.（IF=1.905）

26. Zhou WB, Zhong CN, Luo XP, Zhang YY, Zhang GY, Zhou DX*, Li-ping Liu*, miR-625 suppresses cell proliferation and migration by targeting HMGA1 in breast cancer, Biochem Biophys Res Commun, 2016, 470(4):838-844.（IF=2.466）

27. Li-ping Liu#, Hui-fang Liang#, Xiao-ping Chen*, Wan-guang Zhang, Sheng-li Yang, Tao Xu, and Li Ren. The role of NF-kappaB in Hepatitis b virus X protein-mediated upregulation of VEGF and MMPs. Cancer Invest, 2010, 28(5):443-451. （IF= 2.007）

28. Li-ping Liu#, Yang M, Peng QZ, Li MY, Zhang YS, Guo YH, Chen Y, Bao SY. UBE2T promotes hepatocellular carcinoma cell growth via ubiquitination of p53. Biochem Biophys Res Commun. 2017;493(1):20-27.（IF= 2.466）

29. Qiao L, Zhang Q, Sun Z, Liu Q, Wu Z, Hu W, Bao S, Yang Q, 25. Li-ping Liu. The E2F1/USP11 positive feedback loop promotes hepatocellular carcinoma metastasis and inhibits autophagy by activating ERK/mTOR pathway. Cancer Letter, 2021, 514:63-78.

发明专利

1. 刘利平、刘权、严巧婷、王斗、葛晨晨、张玉华、鲍世韵，一种用于癌症治疗的光纳米疫苗及其制备方法和应用，专利号：ZL201980003493.5，授权公告日：2022年09月30日

2. 刘利平、刘权、孙哲、吕孔鹏、张强弩、石露林、鲍世韵，一种光敏材料和指标方法及其在肿瘤光热联合免疫治疗中的应用，专利号：ZL202110671876.9，授权公告日：2023年03月17日

3. 刘利平、张强弩、刘权、严巧婷、张育森、孙哲、鲍世韵，一种基于RNA结合蛋白基因的肝细胞癌预后评分系统及其应用，专利号：ZL202110172416.1，授权公告日：2023年10月03日

4. 刘利平、孙哲、刘权，一种硼烯纳米疫苗及其制备方法和应用，专利号：ZL202110646317.2，授权公告日：2023年08月18日

5. 吴美龙，刘利平，调控器官脉管流量的装置，专利号：ZL202320593814.5，授权公告日：2023年08月11日

专利转化

1. 吴美龙，刘利平，调控器官脉管流量的装置，专利号：ZL202320593814.5，受让方：徐州必晟智能感知技术研究有限公司，转让金额：500万元，转让时间：2025年4月24日。