临床双聘教授

发表文章

1) Nana Jin#, Chuanchuan Nan#, Wanyang Li#, Peijing Lin, Yu Xin, Jun Wang, Yuelong Chen, Yuanhao Wang, Kaijiang Yu, Changsong Wang, Chunbo Chen*, Qingshan Geng*, Lixin Cheng*. PAGE-based transfer learning from single-cell to bulk sequencing enhances model generalization for sepsis diagnosis. Briefings in Bioinformatics, 2025. （小类一区，IF=7.7）

2) Dian Meng, Yu Feng, Kaishen Yuan, Zitong Yu, Qin Cao Lixin Cheng∗, Xubin Zheng∗. scMMAE: masked cross-attention network for single-cell multimodal omics fusion to enhance unimodal omics. Briefings in Bioinformatics, 2025. （小类一区，IF=7.7）

3) Pengfei Huang#, Yanqi Liu#, Yue Li#, Yu Xin#, Chuanchuan Nan#, Yinghao Luo, Yating Feng, Nana Jin, Yahui Peng, Dawei Wang, Yang Zhou, Feiyu Luan, Xinran Wang, Xibo Wang, Hongxu Li, Yuxin Zhou, Weiting Zhang, Yuhan Liu, Mengyao Yuan, Yuxin Zhang, Yuchen Song, Yu Xiao, Lifeng Shen, Kaijiang Yu*, Mingyan Zhao*, Lixin Cheng*, Changsong Wang*. Metabolomics- and proteomics-based multiomics integration reveals early metabolite alterations in sepsis-associated acute kidney injury. BMC Medicine, 2025. （一区，IF=7.0）

4) Ran Wang, Yan Qian, Xiaojing Guo, Fangda Song, Zhiqiang Xiong, Shirong Cai, Xiuwu Bian, Man Hon Wong, Qin Cao*, Lixin Cheng*, Kwong Sak Leung*, Gang Lu*. STModule: identifying tissue modules to uncover spatial components and characteristics of transcriptomic landscapes. Genome Medicine, 2025. （一区，IF=10.4）

5) Jiayue Qiu, Nana Jin, Lixin Cheng*, Chen Huang*. iDICss robustly predicts melanoma immunotherapy response by synergizing genomic and transcriptomic knowledge via independent component analysis. Clinical and Translational Medicine, 2025. （一区，IF=7.9）

6) Shuojia Wang, Zikuan Yang, Yilin Chen, Jing Zhu, Lin Kang*, Lixin Cheng*. Longitudinal association between multimorbidity, participating activity and cognitive function: cross-lagged mediation analysis. The Journals of Gerontology: Series A, 2025. （二区，IF=4.3）

7) Meijun Liu#, Yuying Wang#, Xiaoli Chen#, Yu Zeng#, Wenqiong Huang, Jiawen Yang, Hong Dai, Lixin Cheng*, Claudio Mauro*, Kenneth Chat Pan Cheung*. A novel approach to enhance glioblastoma multiforme treatment efficacy: non-coding RNA targeted therapy and adjuvant approaches. Clinical Epigenetics, 2025. （二区，IF=4.4）

8) Mengyang Jia, Xiyu Chen, Chen Liang, Shuojia Wang, Cheng Jiang, Yupeng Zeng, Xin Jiang*, Lixin Cheng*, Qingshan Geng*. The association between depressive symptom trajectories and risk of all-cause mortality and premature death: A 10-year follow-up study in United States and England. General Hospital Psychiatry, 2025. （二区，IF=3.7）

9) Chuanchuan Nan#, Ning Zhang#, Haonan Wu, Yuxin Chen, Pengfei Huang, Chenqing Zheng, Nana Jin, Shuojia Wang, Xia Zhang, Xubin Zheng, Changsong Wang, Chunbo Chen⁎, Lixin Cheng*. Toward Pan-Age Sepsis Detection: Leveraging Pediatric Transcriptome Data to Enhance Diagnostic Model Generalizability in Heterogeneous Populations. Fundamental Research, 2025. （二区，IF=6.3）

10) Shuojia Wang, Yilin Chen, Lijiao Xiong, Nana Jin, Pengfei Zhao, Zhen Liang*, Lixin Cheng*, Lin Kang*. Multimorbidity measures associated with cognitive function among community dwelling older Chinese adults. Alzheimer’s & Dementia. 2024. （一区，IF=11.1）

11) Xubin Zheng, Dian Meng, Duo Chen, Wan-Ki Wong, Ka-Ho To, Lei Zhu, JiaFei Wu, Yining Liang, Kwong-Sak Leung, Man-Hon Wong, and Lixin Cheng*. scCaT: An explainable capsulating architecture for sepsis diagnosis transferring from single-cell RNA sequencing. PLOS Computational Biology, 2024. （二区，IF=3.6）

12) Ning Zhang#, Fengxia Yang#, Pengfei Zhao#, Nana Jin, Haonan Wu, Tao Liu, Qingshan Geng*, Xiaojun Yang*, and Lixin Cheng*. MrGPS: a m6A-related gene pair signature to predict the prognosis and immunological impact of glioma patients. Briefings in Bioinformatics, 2024. （小类一区，IF=7.7）

13) Ying Li#, Jing Gao#, Xubin Zheng#, Guole Nie, Jican Qin, Haiping Wang, Tao He, Åsa Wheelock, Chuan-Xing Li*, Lixin Cheng*, Xun Li*. Diagnostic prediction of portal vein thrombosis in chronic cirrhosis patients using data-driven precision medicine model. Briefings in Bioinformatics, 2024. （小类一区，IF=7.7）

14) Jun Wang, Marc Horlacher, Lixin Cheng*, Ole Winther*. DeepLocRNA: An Interpretable Deep Learning Model for Predicting RNA Subcellular localisation with domain-specific transfer-learning. Bioinformatics, 2024. （三区，IF=5.4）

15) Shuojia Wang, Chengyuan Yu, Jing Zhu, Pengfei Zhao, Nana Jin, Lixin Cheng*, Lin Kang*. Multimorbidity patterns, leisure activities, and cognitive function: A population-based longitudinal study. The Journals of Gerontology: Series A, 2024. （二区，IF=4.3）

16) Jize Xie#, Xubin Zheng#, Jianlong Yan#, Qizhi Li, Nana Jin, Shuojia Wang, Pengfei Zhao, Shuai Li, Wanfu Ding*, Lixin Cheng*, Qingshan Geng*. Deep learning model to discriminate diverse infection types based on pairwise analysis of host gene expression. iScience, 2024. （二区，IF=4.1）

17) Qizhi Li#, Xubin Zheng#, Jize Xie#, Ran Wang, Mengyao Li, Man-Hon Wong, Kwong-Sak Leung, Shuai Li, Qingshan Geng*, and Lixin Cheng*. bvnGPS: a generalizable diagnostic model for acute bacterial and viral infection using integrative host transcriptomics and pretrained neural networks. Bioinformatics, 2023.（二区，IF=6.9）

18) Lixin Cheng^#*, Haonan Wu^#, Xubin Zheng, Ning Zhang, Pengfei Zhao, Ran Wang, Qiong Wu, Tao Liu, Xiaojun Yang, and Qingshan Geng*. GPGPS: a robust prognostic gene pair signature of glioma ensembling IDH mutation and 1p/19q co-deletion. Bioinformatics, 2023. （二区，IF=6.9）

19) Ran Wang, Xubin Zheng, Fangda Song, Man Hon Wong, Kwong Sak Leung, and Lixin Cheng*. Deciphering associations between gut microbiota and clinical factors using microbial modules. Bioinformatics, 2023. （二区，IF=6.9）

20) Xiaojun Liu#, Chengyin Hong#, Yichun Jiang#, Wei Li, Youlian Chen, Yonghui Ma, Pengfei Zhao, Tiyuan Li, Huaisheng Chen*, Xueyan Liu*, and Lixin Cheng*. Co-expression module analysis reveals high expression homogeneity for both coding and non-coding genes in sepsis. BMC Genomics, 2023. （二区，IF=4.4）

21) Qiong Wu#, Xubin Zheng#, Kwong-Sak Leung, Man-Hon Wong, Stephen Kwok-Wing Tsui*, and Lixin Cheng*. meGPS: a multi-omics signature for hepatocellular carcinoma detection integrating methylome and transcriptome data. Bioinformatics, 2022. （二区，IF=6.9）

22) Ran Wang, Xubin Zheng, Jun Wang, Shibiao Wan, Fangda Song, Man-Hon Wong, Kwong-Sak Leung, and Lixin Cheng*. Improving bulk RNA-seq classification by transferring gene signature from single cells in acute myeloid leukemia. Briefings in Bioinformatics, 2022. （小类一区，IF=14）

23) Xueyan Liu, Yong Xu, Ran Wang, Sheng Liu, Jun Wang, YongLun Luo, Kwong-Sak Leung, and Lixin Cheng*. A network-based algorithm for the identification of moonlighting non-coding RNAs and its application in sepsis.  Briefings in Bioinformatics, 2021.（小类一区，IF=11.6）

24) Xubin Zheng, Kwong-Sak Leung, Man-Hon Wong, and Lixin Cheng*. Long non-coding RNA Pairs to Assist in Diagnosing Sepsis. BMC Genomics, 2021.（二区，IF=3.6）

25) Yueran Yang#, Yu Zhang#, Shuai Li, Xubin Zheng, Man-Hon Wong, Kwong-Sak Leung, and Lixin Cheng*. A robust and generalizable immune-related signature for sepsis diagnostics. IEEE/ACM Trans Comput Biol Bioinform, 2021. （三区，IF=3.4）

26) Honglong Wu, Xuebin Wang, Mengtian Chu, Dongfang Li, Lixin Cheng*, Ke Zhou*. HCMB: A stable and efficient algorithm for processing the normalization of highly sparse Hi-C contact data. Computational and Structural Biotechnology Journal, 2021.（二区，IF=7.2）

27) Lixin Cheng*#, Yonglun Zeng#, Shuai Hu, Ning Zhang, Kenneth C.P. Cheung, Baiying Li, Kwong-Sak Leung, Liwen Jiang*. Systematic prediction of autophagy-related proteins using Arabidopsis thaliana interactome data. Plant Journal, 2021. （一区，IF=6.4）

28) Xueyan Liu#, Xubin Zheng#, Jun Wang#, Ning Zhang, Kwong-Sak Leung, Xiufeng Ye*, and Lixin Cheng*. A long non-coding RNA signature for diagnostic prediction of sepsis upon ICU admission. Clinical and Translational Medicine, 2020.（一区，IF=7.9）

29) Linting Li#, Min Liu#, Ludan Yue#, Rui Wang, Ning Zhang, Yujie Liang, Liang Zhang, Lixin Cheng*, Jiang Xia*, Ruibing Wang*. Host–Guest Protein Assembly for Affinity Purification of Methyllysine Proteomes. Analytical Chemistry, 2020.（一区，Nature index，IF=6.8）

30) Sheng Liu, Wenjing Zhao, Xueyan Liu*, and Lixin Cheng*. Metagenomic analysis of the gut microbiome in atherosclerosis patients identify cross-cohort microbial signatures and potential therapeutic target. FASEB J. 2020. （二区，IF=4.9）

31) Lixin Cheng#, Chuanchuan Nan#, Lin Kang#, Ning Zhang, Sheng Liu, Huaisheng Chen, Chengying Hong, Youlian Chen, Zhen Liang*, Xueyan Liu*. Whole blood transcriptomic investigation identifies long non-coding RNAs as regulators in sepsis. Journal of Translational Medicine, 2020. （二区，IF=4.1）

32) Jun Wang, Xi Xiang, Lars Bolund, Xiuqing Zhang, Lixin Cheng*, Yonglun Luo*. GNL-Scorer: A generalized model for predicting CRISPR on-target activity by machine learning and featurization. Journal of Molecular Cell Biology, 2019. （一区，IF=4.7）

33) Xueyan Liu#, Nan Li#, Sheng Liu, Jun Wang, Ning Zhang, Xubin Zheng, Kwong-Sak Leung, Lixin Cheng*. Normalization methods for the analysis of unbalanced transcriptome data: a review. Frontiers in Bioengineering and Biotechnology, 2019.（二区，IF=5.1）

34) Lixin Cheng*, Kwong-Sak Leung*. Identification and characterization of moonlighting long non-coding RNAs based on RNA and protein interactome. Bioinformatics, 2018.（二区，IF=7.3）

35) Lixin Cheng*, Kwong-Sak Leung*. Quantification of non-coding RNA target localization diversity and its application in cancers. Journal of Molecular Cell Biology, 2017.（一区，IF=6.0）

发明专利

（1）超声辅助诊断方法及系统（专利号：ZL202510560880.6），发明人：蔡进中;苏伟珠;蒋勇;杨文涛;程立新:陈朝晖;刘明;龚炜，授权日期：2025年07月01日；

（2）医疗机器人操作控制方法及系统（专利号：ZL202510527733.9），发明人：蔡进中;苏伟珠;蒋勇:杨文涛;程立新;陈朝晖;刘明;龚炜，授权日期：2025年07月04日